Effects of fullerene (C60) on antioxidant enzyme activities and lipid peroxidation in gill of the cichlid fish, Pseudetroplus maculatus (Bloch, 1795)

Sumi N Chitra KC      

Abstract

Fullerene (C60) nanomaterials possessing unique physicochemical and biological properties are extensively used in the medical and industrial applications. The aim of the study was to evaluate the effects of fullerene on the antioxidant enzyme activities in gill of cichlid fish, Pseudetroplus maculatus. Fullerene at 0.1 mg/ L concentration was exposed to fish for 24, 48, 72 and 96 h maintaining control groups. The activities of antioxidant enzyme was estimated in gill tissue and it was observed with significant (P<0.05) reduction in the activities of catalase and glutathione reductase. However, the levels of hydrogen peroxide generation and lipid peroxidation was increased in the treatment groups with a significant (P<0.05) increase at the end of 72 and 96 h. Acid and alkaline phosphatases, the reliable indicator of environmental stress to aquatic organisms are also evaluated and the results showed that fullerene significantly decreased the activities of phosphatases in gill of fish in all treatment groups. The present study therefore confirms that fullerene at acute exposure is known to induce oxidative stress and alter the membrane transport across the gill tissue.


MS Received Date:   2016-12-22  MS Accepted Date:  2017-01-11  MS Published Date:  2017-01-13
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Sumi N, Chitra KC. "Effects of fullerene (C60) on antioxidant enzyme activities and lipid peroxidation in gill of the cichlid fish, Pseudetroplus maculatus (Bloch, 1795)" Journal of Zoology Studies 3.6 (2016): 31-37.
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Sumi, N., Chitra, KC. (2016). Effects of fullerene (C60) on antioxidant enzyme activities and lipid peroxidation in gill of the cichlid fish, Pseudetroplus maculatus (Bloch, 1795). Journal of Zoology Studies, 3(6), 31-37.
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Sumi N, Chitra KC. Effects of fullerene (C60) on antioxidant enzyme activities and lipid peroxidation in gill of the cichlid fish, Pseudetroplus maculatus (Bloch, 1795). Journal of Zoology Studies. 2016; 3(6): 31-37.
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