Toxic effects of copper on hematological and enzymatic responses of fresh water catfish Clarias batrachus (Linn.)

Kumar M Raj A Devi S     

Abstract

The aim of this study was investigating hematological and enzymatic effects of Cu on C. batrachus. Freshwater fish Clarias batrachus were exposed to sublethal concentrations of copper for short and long terms. Responses of hematological parameters which include red blood cells count (RBC) and hemoglobin content (Hb) were investigated. Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities were also determined. The aquaria were divided into two groups: the first group was exposed for one week to 2, 4 and 6 mg/L of CuSO4 which represent 0.3, 0.5 and 0.7 of Cu LC50, respectively with three replicates for each concentration, in addition to 0.00 LC50 as the control; while the second group was exposed to the same concentrations of CuSO4 with the same replicates for 4 weeks. The results of hematological parameters indicated that RBC and HB were significantly increased with increasing the concentration of CuSO4 sequentially for both short and long exposure periods. The enzymatic estimation showed that the activity of AST and ALT also significantly increased sequentially in copper treated fish at both exposure periods. Results of the present study suggest that sublethal concentrations of copper affect the hematological changes and impaired liver functions. These parameters can be useful in environmental biomonitoring of copper contamination.


MS Received Date:   2017-01-15  MS Accepted Date:  2017-04-20  MS Published Date:  2017-04-26
Downloads:  269  Views:  248


Download Pdf
Kumar M, Raj A., Devi S. "Toxic effects of copper on hematological and enzymatic responses of fresh water catfish Clarias batrachus (Linn.)" Journal of Zoology Studies 4.1 (2017): 31-36.
Citation in MLA Format
Kumar, M., Raj, A., Devi, S. (2017). Toxic effects of copper on hematological and enzymatic responses of fresh water catfish Clarias batrachus (Linn.). Journal of Zoology Studies, 4(1), 31-36.
Citation in APA Format
Kumar M, Raj A, Devi S. Toxic effects of copper on hematological and enzymatic responses of fresh water catfish Clarias batrachus (Linn.). Journal of Zoology Studies. 2017; 4(1): 31-36.
Citation in Vancouver Format
Creative Commons License