Exposure to chlorpyrifos altered histoarchitecture of hepatocytes in the freshwater fish, Pseudetroplus maculatus (Bloch, 1795)

Raibeemol KP Chitra KC      

Abstract

Chlorpyrifos (O,O-Diethyl–O–3,5,6–trichloro-2-pyridyl phosphorothioate) is an organophosphate pesticide widely used in agriculture and aquaculture. Chlorpyrifos at sublethal concentration (0.661 µg/ L) was exposed to the cichlid fish, Pseudetroplus maculatus for 24, 48, 72 and 96 h. At the end of every treatment period, liver tissue was collected and examined for structural modifications. The hepatic alterations observed due to chlorpyrifos treatment were necrosis, vacuolization, segmentation of hepatic cells, anucleated cells, pyknotic nuclei of the cell, degenerative cytoplasm, melano macrophage aggregation and few spindle shaped nucleus. These hepatic alterations were more prominent in fish when exposed to chlorpyrifos for longer durations. In the present investigation, Pseudetroplus maculatus is used as biological indicator to assess aquatic pollution, which clearly demonstrates that chlorpyrifos altered the histoarchitecture of hepatocytes in fish. Therefore, chlorpyrifos could be considered as extremely toxic chemical when exposed to aquatic organisms even at sublethal concentration.


MS Received Date:   2017-07-28  MS Accepted Date:  2017-08-18  MS Published Date:  2017-08-22
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Raibeemol KP, Chitra KC. "Exposure to chlorpyrifos altered histoarchitecture of hepatocytes in the freshwater fish, Pseudetroplus maculatus (Bloch, 1795)" Journal of Zoology Studies 4.4 (2017): 18-22.
Citation in MLA Format
Raibeemol, KP., Chitra, KC. (2017). Exposure to chlorpyrifos altered histoarchitecture of hepatocytes in the freshwater fish, Pseudetroplus maculatus (Bloch, 1795). Journal of Zoology Studies, 4(4), 18-22.
Citation in APA Format
Raibeemol KP, Chitra KC. Exposure to chlorpyrifos altered histoarchitecture of hepatocytes in the freshwater fish, Pseudetroplus maculatus (Bloch, 1795). Journal of Zoology Studies. 2017; 4(4): 18-22.
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